Commonly Used Intracameral Antibiotics for Endophthalmitis Prophylaxis: A Literature Review

Endophthalmitis is a serious complication of cataract surgery that occurs in thousands of patients each year. To decrease the incidence of post-operative endophthalmitis, many surgeons inject intracameral antibiotics (cefuroxime, moxifloxacin, and vancomycin) routinely at the conclusion of surgery. A large number of recently published retrospective studies and large database analyses have reported decreased endophthalmitis rates with routine antibiotic use, and the only prospective, multi-center, randomized trial performed by the European Society of Cataract and Refractive Surgery demonstrated that intracameral cefuroxime decreases the incidence of post-operative endophthalmitis.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Major review Source Type: research