THE SURFACE MICROBIOME OF CLINICALLY UNAFFECTED SKINFOLDS IN HIDRADENITIS SUPPURATIVA: A CROSS-SECTIONAL CULTURE BASED AND 16S rRNA GENE AMPLICON SEQUENCING STUDY IN 60 PATIENTS.

Hidradenitis Suppurativa (HS) is a chronic inflammatory disease of the skin associated with specific lesional dysbiotic features. We studied the microbiome of clinically unaffected typical HS sites (armpits, inguinal folds and gluteal clefts) in 60 HS patients and 17 healthy controls.192 samples obtained by swabbing were analyzed by bacterial cultures. 116 randomly selected samples were studied by 16S rRNA gene amplicon sequencing. Patients and controls showed similar characteristics, except for smoking (87% vs 6%, respectively).

Source: Journal of Investigative Dermatology - April 23, 2020 Category: Dermatology Authors: Émeline Riverain-Gillet, Hélène Guet-Revillet, Jean-Philippe Jais, Marie-Noëlle Ungeheuer, Sabine Duchatelet, Maïa Delage, Thi Lam, Alain Hovnanian, Aude Nassif, Olivier Join-Lambert Tags: Original Article Source Type: research