Round Spermatid Injection.
Round Spermatid Injection.
Urol Clin North Am. 2020 May;47(2):175-183
Authors: Gross KX, Hanson BM, Hotaling JM
Abstract
From a fertility perspective, men with azoospermia represent a challenging patient population. When no mature spermatozoa are obtained during a testicular sperm extraction, patients are often left with limited options, such as adoption or the use of donor sperm. However, it has been reported that round spermatids can be successfully injected into human oocytes and used as an alternative to mature spermatozoa. This technique is known as round spermatid injection (ROSI). Despite the limitations of ROSI and diminished clinical success rates, the use of round spermatids for fertilization may have potential as a treatment modality for men with azoospermia.
PMID: 32272989 [PubMed - in process]
Source: The Urologic Clinics of North America - Category: Urology & Nephrology Authors: Gross KX, Hanson BM, Hotaling JM Tags: Urol Clin North Am Source Type: research