Defining the prognostic role of microRNAs in cutaneous melanoma

Breslow thickness (BT) is the most important histopathologic factor for primary melanoma staging. Breslow thickness determines the margins for wide local excision, whether sentinel lymph node biopsy should be performed and subsequent melanoma staging and patient management. The correct determination of a 0.8 mm cut-off in melanoma is important for pathologists since discrepancies leading to a change in stage can have significant clinical implications, including incorrect/inappropriate prognostic information, investigation, management and follow-up.

Source: Journal of Investigative Dermatology - April 6, 2020 Category: Dermatology Authors: Emi Dika, Mattia Riefolo, Elisa Porcellini, Elisabetta Broseghini, Simone Ribero, Rebecca Senetta, Simona Osella Abate, Federica Scarfi, Martina Lambertini, Giulia Veronesi, Annalisa Patrizi, Pier Alessandro Fanti, Manuela Ferracin Tags: Original Article Source Type: research