Evaluation of low-volume post-dilution online hemodiafiltration with Japanese high-performance hemodiafilters

AbstractTo assess the removal performance of low-volume post-hemodiafiltration (HDF) with Japanese hemodiafilters and the removal performance with 20  % reduction in the total dialysate flow rate (Qdtotal). Subjects were 8 patients undergoing pre-HDF. Study 1: Post-HDF was performed at a blood flow rate (Qb) of 250  mL/min and a total volume of substitution fluid (Vs) of 12 L/session(s) for 4 hrs using Fineflux-210Seco (FIX), ABH-21PA (ABH), and NVF-21H (NVF). We assessed removal efficiency of small molecular solutes, low-molecular-weight-proteins and the amount of albumin loss. Study 2: Post-HDF was perfor med at Vs of 12 L/s under G-1,Qdtotal of 500 andQb of 250  mL/min; G-2,Qdtotal of 400 andQb of 250  mL/min; and G-3,Qdtotal of 400 andQb of 300  mL/min. Removal efficiency was compared and analyzed between these conditions. Subjects were 8 patients undergoing pre-HDF. Study 1: Post-HDF was performed at a blood flow rate (Qb) of 250  mL/min and a total volume of substitution fluid (Vs) of 12 L/session(s) for 4 hrs using Fineflux-210Seco (FIX), ABH-21PA (ABH), and NVF-21H (NVF). We assessed removal efficiency of small molecular solutes, low-molecular-weight-proteins and the amount of albumin loss. Study 2: Post-HDF was perfor med at Vs of 12 L/s under G-1,Qdtotal of 500 andQb of 250  mL/min; G-2,Qdtotal of 400 andQb of 250  mL/min; and G-3,Qdtotal of 400 andQb of 300  mL/min. Removal efficiency was compared and analyzed between these conditions. Study 1: The res...
Source: Journal of Artificial Organs - Category: Transplant Surgery Source Type: research