MRI features help predict breast cancer prognosis

Certain features on dynamic contrastl-enhanced (DCE) MRI scans analyzed computer-aided...Read more on AuntMinnie.comRelated Reading: Shorter MRI works for patients with breast cancer history Breast MRI works as presurgical tool Patients want sensitive adjunct breast screening 10-minute breast MRI scan beats DBT for invasive cancer MRI finds cancer missed on clinical breast exams
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Conclusions: This proof-of-concept study demonstrates that high-resolution FDG-PET/CT can facilitate intra-operative margin assessment during BCS. This technique achieves good sensitivity and specificity and may therefore reduce re-operation rates in the future. PMID: 32452298 [PubMed - as supplied by publisher]
Source: Acta Chirurgica Belgica - Category: Surgery Tags: Acta Chir Belg Source Type: research
Breast MRI can produce more false positives on initial screening in women at...Read more on AuntMinnie.comRelated Reading: Bilateral breast MRI needed even after mastectomy Who gets breast cancer treatment during a pandemic? MRI features help predict breast cancer prognosis Shorter MRI works for patients with breast cancer history Breast MRI works as presurgical toolComments: 5/28/2020 3:40:02 AMDaniel Corcos Many high-risk women carry mutations in genes involved in the repair of DNA breaks caused by X-rays. As mammography screening leads to a high cancer incidence in the general population (Corcos &Bleyer,...
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
By MICHEL ACCAD Last month marked the 400th anniversary of the birth of John Graunt, commonly regarded as the father of epidemiology.  His major published work, Natural and Political Observations Made upon the Bills of Mortality, called attention to the death statistics published weekly in London beginning in the late 16th century.  Graunt was skeptical of how causes of death were ascribed, especially in times of plagues.  Evidently, 400 years of scientific advances have done little to lessen his doubts!  A few days ago, Fox News reported that Colorado governor Jared Polis ...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: COVID-19 Medical Practice Physicians Diagnosis MICHEL ACCAD Source Type: blogs
Fluorescent silica nanoparticles (SNPs) are introduced as a robust labeling strategy to visualize tumor cells within mineralized bone from in vitro and in vivo studies. SNP labeling efficiency of MDA ‐MB‐231 breast cancer cells is characterized using a broad range of bone processing and imaging techniques. SNPs are tools with the potential to increase the understanding of mineral contributions to bone metastasis. AbstractDuring breast cancer bone metastasis, tumor cells interact with bone microenvironment components including inorganic minerals. Bone mineralization is a dynamic process and varies spatiotemporally as a ...
Source: Small - Category: Nanotechnology Authors: Tags: Full Paper Source Type: research
CONCLUSION: Bone scans improved in 38% of patients with metastatic hormone receptor positive breast cancer and remained stable in an additional 12% for a minimum duration of 12 weeks on cabozantinib. Further investigations should assess the activity of cabozantinib in combination with other hormonal and other breast cancer therapies and determine whether bone scan responses correlate with meaningful antitumor effects. IMPLICATION FOR PRACTICE: Most patients with metastatic hormone receptor positive (HR+) breast cancer have bone involvement, and many have bone-only disease which is difficult to evaluate for resp...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
In conclusion, the combination of continuous dosing of veliparib and every-3-week carboplatin demonstrated activity and an acceptable toxicity profile. Decrease in SUVmax on 18 FLT-PET scan during the first cycle of this therapy can identify patients who are likely to have a response. IMPLICATIONS FOR PRACTICE: The BROCADE studies suggest that patients with BRCA mutation benefit from addition of the poly(ADP-ribose) polymerase inhibitor veliparib to carboplatin plus paclitaxel. This study demonstrates that a higher dose of veliparib is tolerable and active in combination with carboplatin alone. With growing interest in ima...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
Abstract BACKGROUND AND PURPOSE: To compare secondary malignancy risks of modern proton and photon therapy techniques for locally advanced breast cancer. METHODS AND MATERIALS: We utilized dosimetric data from 34 [10 photon-VMAT, 10 photon-3DCRT, 14 pencil beam scanning proton (PBS)] breast cancer patients who received comprehensive nodal irradiation. Employing a model based on organ equivalent dose to account for both inhomogeneous organ dose distributions and non-linear functional dose relationships, we estimated excess absolute risk, excess relative risk, and lifetime attributable risk (LAR) for secondary ...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
Abstract An electrochemical biopsy probe was designed and fabricated to detect cancer tumors under the sonography guide without the need for any sample dissection (biopsy). The system was based on recording the hypoxic function of cancer tumors by Multi-wall carbon nanotubes (MWCNTs) sensing agents had been decorated on the tip of the needle electrodes by an electrostatic deposition method. This system named BGP successfully distinct 4T1 and MC4L2 breast tumors from normal lesions. It also diagnosed the treated tumors from vital ones. BGP as a clinically useful biosensor would detect the cancerous probability of a...
Source: Biosensors and Bioelectronics - Category: Biotechnology Authors: Tags: Biosens Bioelectron Source Type: research
ConclusionsThe restaging of patients who had ER-positive primary breast cancer and present with recurrent disease may include [18F]FES PET/CT as an initial test when standard imaging studies are equivocal or suspicious.
Source: EJNMMI Research - Category: Radiology Source Type: research
The authors tested the use of tablets to collect breast cancer risk data and compared the approach against paper-based scantrons. The goal was to examine the usability of digital technology for data collection in underserved populations. A total of 340 individuals were randomized to answer a breast health survey via either tablets (170) or paper forms (170). Post questionnaire surveys were conducted to evaluate the usability of tablets. Outcomes included completion time, satisfaction, and the numbers and types of questions raised by patients during the survey. There was no significant difference in questionnaire completion...
Source: International Journal of E-Health and Medical Communications - Category: Information Technology Authors: Tags: Health Information Systems Medicine & Healthcare Source Type: research
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