Vanishing vessels aboding pulmonary disease: a role for VEGFR2

There is growing recognition for the involvement of blood vessels in pulmonary diseases beyond the classical scope of pulmonary vascular medicine. As an example, reports have described a vascular phenotype of COPD, or have proposed a vanishing pulmonary capillary syndrome to underly emphysema [1, 2]. Although the number of clinical and epidemiological studies supporting such a vascular hypothesis of pulmonary disease is steadily growing, biological underpinning in clinical studies remains to be provided.

Source: European Respiratory Journal - April 2, 2020 Category: Respiratory Medicine Authors: Botros, L., Vonk Noordegraaf, A., Aman, J. Tags: Editorials Source Type: research