Latest autism research makes progress toward biomarkers

In Autism Awareness Month, we take a look at varied studies whose findings point to potential biomarkers for the disorder. (read more)
Source: Environmental Factor - NIEHS Newsletter - Category: Environmental Health Source Type: news

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Publication date: Available online 28 May 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Way K.W. Lau, Mei-Kei Leung, Ruibin Zhang
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Authors: Andrade C Abstract In observational studies, significant associations have often been identified between antidepressant drug prescription during pregnancy, on the one hand, and autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), on the other. Interpreting these associations is problematic because they are based on analyses that could not adjust for inadequately measured, unmeasured, and unknown confounds. Recent clinical data suggest that a genetic relationship exists between depression and neurodevelopmental disorders. A very recent study identified many genetic loci that w...
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
Authors: Bugyi B, Kengyel A Abstract Myosin XVI (Myo16), a vertebrate-specific motor protein, is a recently discovered member of the myosin superfamily. The detailed functionality regarding myosin XVI requires elucidating or clarification; however, it appears to portray an important role in neural development and in the proper functioning of the nervous system. It is expressed in the largest amount in neural tissues in the late embryonic-early postnatal period, specifically the time in which neuronal cell migration and dendritic elaboration coincide. The impaired expression of myosin XVI has been found lurking in t...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
             Basel, 28 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced European Medicines Agency (EMA) approval of a new, shorter two-hour OCREVUS ® (ocrelizumab) infusion time, dosed twice yearly, for relapsing or primary progressive multiple sclerosis (MS). The approval is based on a positive opinion from the EMA’s Committee for Medicinal Products for Human Use (CHMP).“The approval of a shorter, two-hour infusion time for OCREVUS in Europe, dosed twice yearly, will further improve the treatment experience for patients while als...
Source: Roche Media News - Category: Pharmaceuticals Source Type: news
Mucus is integral to gut health and its properties may be affected in neurological disease. Mucus comprises a hydrated network of polymers including glycosylated mucin proteins. We propose that factors that influence the nervous system may also affect the volume, viscosity, porosity of mucus composition and subsequently, gastrointestinal (GI) microbial populations. The gut has its own intrinsic neuronal network, the enteric nervous system, which extends the length of the GI tract and innervates the mucosal epithelium. The ENS regulates gut function including mucus secretion and renewal. Both dysbiosis and gut dysfunction a...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
A child with an uncle or aunt with autism appears to have a more than doubled risk of being diagnosed with an autism spectrum disorder themselves, a new U.S. government-funded study reports.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Shutterstock Is it fair to question a presidential candidate’s mental fitness? (Salon): “My heart sank as he floundered his way through his responses, fumbling with his notes, uncharacteristically lost for words. He looked tired and bewildered,” Ron Reagan, the son of President Ronald Reagan, wrote of his father’s performance during the first 1984 presidential debate. At the time, there had long been rumors that Reagan was suffering from cognitive impairment — perhaps Alzheimer’s Disease — and as he struggled during the first debate against his Democratic opponent, former Vice Pres...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Technology Alzheimers-disease Cognitive-impairment mental health mental illness mental-fitness Source Type: blogs
Zynerba Pharmaceuticals Inc., a developer of synthetic cannabinoid therapies, posted positive study results Wednesday from mid-stage testing of its experimental autism spectrum disorder treatment. The Devon company's stock, which closed Tuesday at $6.19 per share, was up 15% at one point in premarket trading before settling back to $6.32 per share when the market opened. The increase came after Zynerba (NASDAQ: ZYNE) released the positive results of a phase-II study testing its lead new dr ug candidate…
Source: Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
WEDNESDAY, May 27, 2020 -- A child with an uncle or aunt with autism appears to have a more than doubled risk of being diagnosed with an autism spectrum disorder themselves, a new U.S. government-funded study reports. Roughly 3% to 5% of children...
Source: - Daily MedNews - Category: General Medicine Source Type: news
Source: Child and Adolescent Psychiatric Clinics of North America - Category: Psychiatry Authors: Source Type: research
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