Risk Factors for Cirrhosis in Contemporary Hepatology Practices —Findings from Texas Hepatocellular Carcinoma Consortium Cohort

Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research

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Conclusion: The results of this survey indicated that 32.05% of HIV patients were positive for HCV Ab, among them 24.35% were positive HCV RNA. HCV genotype 3a was dominant and detected in the three males IDU. Regarding the consequences of HIV/HCV co-infection, it is suggested that HCV RNA detection should be regularly checked in individuals infected with HIV. PMID: 32494350 [PubMed]
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
CONCLUSIONS: The present meta-analysis suggests that aflatoxin exposure is associated with a higher risk of liver cirrhosis. PMID: 32487162 [PubMed - in process]
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Tags: BMC Pharmacol Toxicol Source Type: research
In this study, we investigated long ‐term survival of cirrhotic patients without hepatocellular carcinoma (HCC) and the proper timing of liver transplantation in the era with recent progress of management.Patients and MethodsWe first classified 217 non ‐transplant cirrhotic patients without HCC according to the long‐term survival based on Child‐Turcotte‐Pugh (CTP) scores and the MELD scores. And then, we compared them with the survival after liver transplantation in 114 patients with liver cirrhosis.ResultsWe classified into 4 groups (class A as CTP score of 5,6, B as 7,8, C as 9 ‐12, D as 13‐15) according to...
Source: Journal of Hepato-Biliary-Pancreatic Sciences - Category: Gastroenterology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conditions:   Liver Cirrhosis;   Hepatocellular Carcinoma;   Surveillance Interventions:   Diagnostic Test: AFP-L3;   Diagnostic Test: AFP;   Diagnostic Test: PIVKA-II;   Diagnostic Test: Sonography;   Diagnostic Test: CT Sponsors:   Korea University;   Korea Unversity Ansan Hospital;   Soonchunhyang University Hospital;   Korea University Guro Hospital;   The Catholic University of Korea;   Samsung Medical Center;  ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We described the risk of hepatocellular carcinoma (HCC, the commonest form of liver cancer originating in the liver) in Danish outpatients with liver cirrhosis due to harmful alcohol consumption. Accurate data on that risk are important for patient counselling and decisions about screening for HCC. The risk was about 0.7% per year, which is lower than might be expected and suggests that many potentially harmful screening examinations are required for every HCC found through surveillance.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research
AbstractHepatitis C virus (HCV) is considered leading cause of cirrhosis and hepatocellular carcinoma (HCC). We aimed to examine the association of IL-6 and IL-10 single-nucleotide polymorphisms with the progression of chronic HCV (CHC) infection to cirrhosis and HCC. For comparative purposes, four groups were enrolled; chronic HCV group (CHC,n = 22), HCV-related liver cirrhosis group (HCV-LC,n = 22), HCV-related HCC group (HCV-HCC,n = 54), and an apparently healthy control group (controls,n = 48). HCC diagnosis and staging were in concordance to Barcelona Clinic Liver Cancer...
Source: Immunologic Research - Category: Allergy & Immunology Source Type: research
Conclusion The results show that vitamin D status and VDBP levels are associated with liver cirrhosis severity and patients’ mortality, possibly through a proinflammatory immune response.
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research
Conditions:   Liver Cirrhosis;   Hepatocellular Carcinoma;   Surveillance Interventions:   Diagnostic Test: AFP-L3;   Diagnostic Test: AFP;   Diagnostic Test: PIVKA-II;   Diagnostic Test: Sonography;   Diagnostic Test: CT Sponsors:   Korea University;   Korea Unversity Ansan Hospital;   Soonchunhyang University Hospital;   Korea University Guro Hospital;   The Catholic University of Korea;   Samsung Medical Center;  ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Hepatitis B virus (HBV), along with Hepatitis C virus chronic infection, represents a major risk factor for hepatocellular carcinoma (HCC) development. However, molecular mechanisms involved in the development...
Source: Infectious Agents and Cancer - Category: Cancer & Oncology Authors: Tags: Research Article Source Type: research
Prediction models or scores for hepatocellular carcinoma (HCC) risk stratification are needed to guide individualized management of patients with HCV-related cirrhosis, who are increasingly being treated with highly effective and safe direct-acting antivirals (DAAs).1,2
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
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