Validation of Bartonella henselae Western Immunoblotting for Serodiagnosis of Bartonelloses in Dogs [Clinical Veterinary Microbiology]

In this study, the sensitivity and diagnostic accuracy of B. henselae SA2 WB were higher than those of B. henselae SA2 IFA testing. Some B. henselae SA2 immunodominant proteins were recognized by dogs experimentally and naturally infected with Bartonella spp. other than B. henselae. Additional research is necessary to more fully define the utility of WB for the serodiagnosis of canine bartonelloses.

Source: Journal of Clinical Microbiology - March 24, 2020 Category: Microbiology Authors: Neupane, P., Sevala, S., Balakrishnan, N., Marr, H., Wilson, J., Maggi, R., Birkenheuer, A., Lappin, M., Chomel, B., Breitschwerdt, E. B. Tags: Clinical Veterinary Microbiology Source Type: research