Icariin reduces LPS-induced acute lung injury in mice undergoing bilateral adrenalectomy by regulating GR α.

In conclusion, ICA reduces ALI in mice undergoing bilateral ADX by regulating GRα, and no inhibitory effect on hypothalamic pituitary adrenal (HPA) axis.
PMID: 32147435 [PubMed - as supplied by publisher]

Source: European Journal of Pharmacology - March 4, 2020 Category: Drugs & Pharmacology Authors: Sun X, Cheng H, Liu B, Du Y, Dong J, Huang J Tags: Eur J Pharmacol Source Type: research