Saline versus Lactated Ringer ’s Solution The Saline or Lactated Ringer’s (SOLAR) Trial

Conclusions In elective orthopedic and colorectal surgery patients, there was no clinically meaningful difference in postoperative complications with lactated Ringer ’s or saline volume replacement. Clinicians can reasonably use either solution intraoperatively.Editor ’s PerspectiveWhat We Already Know about This TopicInfusion of large volumes of saline causes hyperchloremic metabolic acidosisA recent Cochrane review based on 18 small trials reported that major morbidity and mortality were comparable with perioperative saline or lactated Ringer ’s useWhat This Article Tells Us That Is NewIn a large single-center alternating cohort trial of patients having elective colorectal or orthopedic surgery, there was no clinically meaningful difference in the risk of a composite of in-hospital mortality and major postoperative complications including renal, respiratory, infectious, and hemorrhagic complications
Source: Anesthesiology - Category: Anesthesiology Source Type: research