A Novel Device for Surveillance of Vascular Access Sites for Bleeding

Conditions:   Dialysis; Complications;   Wound Complication;   Catheter Complications;   Hemorrhage;   Bleeding Wound Intervention:   Device: Application of device which monitors for bleeding - Blood Warning Technology with Continuous Hemoglobin sensor (BWATCH) Sponsor:   Changi General Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Authors: Tsai TJ, Chen WC, Huang YT, Yang YH, Feng IC, Wu WC, Hu HM, Wu DC, Hsu PI Abstract Background: Patients with chronic kidney disease (CKD) with or without hemodialysis were considered to have bleeding tendency and higher risk for gastrointestinal (GI) bleeding. Previous studies had documented that hemodialysis may increase the gastroduodenal ulcer bleeding. Few studies evaluated the relationship between CKD and lower GI bleeding. Materials and Methods. An observational cohort study design was conducted. The end-stage renal disease (ESRD) patients receiving regular hemodialysis (dialysis CKD), CKD patients w...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Abstract BACKGROUND: The transradial approach is reportedly associated with reduced bleeding complications and mortality after percutaneous coronary intervention (PCI). It is unknown whether the clinical benefits of transradial vs. transfemoral PCI differ between high bleeding risk (HBR) and non-HBR patients.Methods and Results:After excluding patients with acute myocardial infarction, dialysis, and a transbrachial approach from the 13,087 patients undergoing first PCI in the CREDO-Kyoto Registry Cohort-2, 6,828 patients were eligible for this study. Patients were divided into 2 groups according to bleeding ri...
Source: Circulation Journal - Category: Cardiology Authors: Tags: Circ J Source Type: research
AbstractAn 88-year-old man with congenital hemophilia A developed end-stage renal disease due to microscopic polyangiitis. He was at risk for catheter-related infection because he was taking immunosuppressive agents for the treatment of polyangiitis. He was also unable to manipulate the peritoneal dialysis device. Therefore, hemodialysis using an arteriovenous fistula was induced for renal replacement therapy. Recombinant coagulation factor VIII (1000  IU) was administered via the venous chamber of the hemodialysis circuit 10 min before the end of each hemodialysis session, and nafamostat mesylate (25 mg/h) ...
Source: CEN Case Reports - Category: Urology & Nephrology Source Type: research
Conclusions: Among patients with AF and CrCl 25-30 mL/min, apixaban caused less bleeding than warfarin, with even greater reductions in bleeding than in patients with CrCl>30 mL/min. We observed substantial overlap in the range of exposure to apixaban 5 mg twice daily for patients with or without advanced CKD, supporting conventional dosing in patients with CrCl 25-30 mL/min. Randomized controlled studies evaluating the safety and efficacy of apixaban are urgently needed in patients with advanced CKD, including those receiving dialysis. Clinical Trial Registration: URL: https://ClinicalTrials.gov Unique Identifier: NCT0...
Source: Circulation - Category: Cardiology Authors: Tags: Circulation Source Type: research
Abstract In patients with tuberous sclerosis complex (TSC), renal complications are not limited to bleeding angiomyolipoma (AML); although rare, end-stage renal disease (ESRD) may occur. New treatments (e.g., mammalian target of rapamycin (m-Tor) inhibitors) for AML might influence the epidemiology of ESRD in patients with TSC. In France, 99 patients with TSC from the Renal Epidemiology and Information Network (REIN) registry and having undergone renal replacement therapy (RRT) between 2002 and 2016 were included in the present study. Additional data were collected from the patients' medical charts. The mean&thins...
Source: Journal of Nephrology - Category: Urology & Nephrology Authors: Tags: J Nephrol Source Type: research
AbstractBackgroundThe optimal mitral prosthesis in young patients is unclear. This systematic review and meta ‐analysis were performed to compare outcomes between bileaflet mechanical mitral valve replacement (mMVR) and bioprosthesis mitral valve replacement (bioMVR) for MVR patients aged less than 70 years.MethodsWe searched MEDLINE and EMBASE databases from inception to July 2018 for studies comparing surgical outcomes of mMVR vs bioMVR.ResultsThere were 14 observational studies with 20  219 patients (n = 14 658 mMVR and n = 5561 bioMVR). Patients receiving an mMVR were younger...
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
Abstract BACKGROUND: Data on blood utilization in proximal aortic surgery is limited. We sought to establish quality benchmarks in the pattern of transfusion during elective aortic root replacement. METHODS: The STS Adult Cardiac Surgery Database was queried to identify all patients who underwent primary elective aortic root replacement between July 2014 and June 2017. Multivariable negative binomial regressions were utilized to determine whether perioperative transfusion was associated with demographic and/or procedural factors. Multivariable logistic regression analysis was performed for clinical outcomes. ...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
Conditions:   Dialysis; Complications;   Wound Complication;   Catheter Complications;   Hemorrhage;   Bleeding Wound Intervention:   Device: Application of device which monitors for bleeding - Blood Warning Technology with Continuous Hemoglobin sensor (BWATCH) Sponsor:   Changi General Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Minor bleeding and oozing from a tunnel dialysis catheter (TDC) insertion site is a common occurrence with a prevalence of between 0% to 42% in literature. However, the risk of significant bleed that results in catheter failure is much lower. To alleviate such bleeding complication, interventional radiologist may preferentially choose Lidocaine with epinephrine mixture instead of plain Lidocaine for local anesthetic at the incision site and within the subcutaneous tunnel during the process of insertion of the catheter.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific e-Poster Source Type: research
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