Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

Publication date: 25 February 2020Source: Cell Reports, Volume 30, Issue 8Author(s): Rajiv Kumar, Patrick T. Bunn, Siddharth Sankar Singh, Susanna S. Ng, Marcela Montes de Oca, Fabian De Labastida Rivera, Shashi Bhushan Chauhan, Neetu Singh, Rebecca J. Faleiro, Chelsea L. Edwards, Teija C.M. Frame, Meru Sheel, Rebecca J. Austin, Steven W. Lane, Tobias Bald, Mark J. Smyth, Geoffrey.R. Hill, Shannon E. Best, Ashraful Haque, Dillon Corvino
Source: Cell Reports - Category: Cytology Source Type: research

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Publication date: Available online 3 April 2020Source: Parasitology InternationalAuthor(s): Hirotaka Katahira, Hana Ashida, Mari Kobayashi
Source: Parasitology International - Category: Parasitology Source Type: research
A collaborative study led by Monash University's Biomedicine Discovery Institute (BDI) in Melbourne, Australia, with the Peter Doherty Institute of Infection and Immunity (Doherty Institute), has shown that an anti-parasitic drug already available around the world kills the virus within 48 hours.
Source: World Pharma News - Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
imarães S Abstract Giardia duodenalis is one of the most important and widespread gastrointestinal parasites in the world. Despite its relevance as a causative agent of diarrhea, asymptomatic giardiasis occurs frequently, especially in low resources settings in which children are exposed to many risk factors. Based on microscopic examination and the polymerase chain reaction (PCR) amplification and sequencing of beta-giardin (bg), triose phosphate isomerase (tpi) and glutamate dehydrogenase (gdh) genes, we assessed G. duodenalis occurrence and genetic diversity in isolates of children attending a daycare ce...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
Abstract SUMMARYWhile flagella have been studied extensively as motility organelles, with a focus on internal structures such as the axoneme, more recent research has illuminated the roles of the flagellar surface in a variety of biological processes. Parasitic protists of the order Kinetoplastida, which include trypanosomes and Leishmania species, provide a paradigm for probing the role of flagella in host-microbe interactions and illustrate that this interface between the flagellar surface and the host is of paramount importance. An increasing body of knowledge indicates that the flagellar membrane serves a mult...
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Microbiol Mol Biol Rev Source Type: research
Publication date: Available online 3 April 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Anna M. Pyziel, Aleksander W. Demiaszkiewicz, Barbara Osińska, Izabella Dolka, Krzysztof Anusz, Zdzisław Laskowski
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
(Monash University) Australian Scientists have shown that an anti-parasitic drug already available around the world can kill the virus -- effectively eradicating all genetic material of the virus within 48 hours. Scientists from Monash University in Melbourne showed that a single dose of the drug, Ivermectin, could stop the SARS-CoV-2 virus growing in cell culture -
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
The apicomplexan parasite Theileria parva causes a livestock disease called East coast fever (ECF), with millions of animals at risk in sub-Saharan East and Southern Africa, the geographic distribution of T. parv...
Source: BMC Genomics - Category: Genetics & Stem Cells Authors: Tags: Research article Source Type: research
Eimeria necatrix, the most highly pathogenic coccidian in chicken small intestines, can cause high morbidity and mortality in susceptible birds and devastating economic losses in poultry production, but the under...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
Babesia spp. are apicomplexan parasites which infect a wide range of mammalian hosts. Historically, most Babesia species were described based on the assumed host specificity and morphological features of the intr...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
Rhipicephalus microplus, an invasive tick species of Asian origin and the main vector of Babesia species, is considered one of the most widespread ectoparasites of livestock. The tick has spread from its native h...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
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