Antibiotic treatment and selection for glpK mutations in patients with active tuberculosis disease [Biological Sciences]

We read with great interest the paper by Safi et al. (1) describing frameshifts in glpK’s homopolymeric tract (HT) of seven cytosines (7C) as a potential cause of antibiotic tolerance. These results have implications for tuberculosis (TB) treatment, but other forces than antibiotic pressure may be responsible for the emergence...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Letters Source Type: research