Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection in Women With Dense Breasts

This randomized trial compares the accuracy of screening with abbreviated breast magnetic resonance imaging (MRI) vs digital breast tomosynthesis (DBT) on invasive breast cancer detection rates in women with dense breasts.
Source: JAMA - Category: General Medicine Source Type: research

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Condition:   Breast Cancer Interventions:   Diagnostic Test: Serum Autotaxin;   Radiation: chest x-ray;   Diagnostic Test: Breast ultrasound or mammography;   Diagnostic Test: Histopathological examination of breast mass specimens;   Radiation: Magnetic Resonance Imaging ( MRI) and Bone scan;   Diagnostic Test: Peripheral  haemogram;   Diagnostic Test: Renal and liver functions;   Diagnostic Test: Prothrombin time and concentration;   Diagnostic Test: Cancer Antigen...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsBoth CESM and MRI are effective methods for the detection of breast cancer with high diagnostic sensitivity. The diagnostic performance of CESM appears to be more effective than MRI.
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ño S Abstract Screening plays an important role in women with a high risk of breast cancer. Given this population's high incidence of breast cancer and younger age of onset compared to the general population, it is recommended that screening starts earlier. There is ample evidence that magnetic resonance imaging (MRI) is the most sensitive diagnostic tool, and American and the European guidelines both recommend annual MRI screening (with supplementary annual mammography) as the optimum screening modality. Nevertheless, the current guidelines do not totally agree about the recommendations for MRI screening i...
Source: Radiologia - Category: Radiology Authors: Tags: Radiologia Source Type: research
CONCLUSIONS: There is no single absolute modality for de tecting ALNMs in breast cancers to replace sentinel lymph node biopsy or axillary lymph node dissection. If ALNM is suspected based on PET/CT, axillary lymph node dissection without sentinel lymph node biopsy might be a better option because it is related to high possibilities of ALNM. KEY WORDS: Axillary lymph node metastasis, Magnetic resonance imaging, Ultrasonography, 18F-FDG PET/CT. PMID: 32213685 [PubMed - as supplied by publisher]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
CONCLUSION: CEUS demonstrated good sensitivity in detecting breast cancer, and the combined use with MRI can optimize the diagnostic specificity and accuracy in breast cancer prediction. ADVANCES IN KNOWLEDGE: Few studies have compared the diagnostic efficacy of CEUS and MRI, and this study is the first attempt to seek out the diagnostic values for breast lesions of variable sizes (lesions with ≤20 mm and>20 mm). PMID: 32216631 [PubMed - as supplied by publisher]
Source: The British Journal of Radiology - Category: Radiology Authors: Tags: Br J Radiol Source Type: research
THURSDAY, March 12, 2020 -- Abbreviated magnetic resonance imaging (MRI) is associated with a significantly higher rate of invasive breast cancer detection compared with digital breast tomosynthesis (DBT) among women with dense breasts, according to...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Authors: Mori N, Mugikura S, Miyashita M, Mori Y, Maekawa Y, Nagasaka T, Takase K Abstract PURPOSE: To compare the image quality between turbo spin-echo (TSE)-diffusion weighted imaging (DWI) and single-shot echo-planar imaging (EPI)-DWI, and to verify the diagnostic performance of the apparent diffusion coefficient (ADC) parameters of the two techniques by using histogram analysis in terms of differentiation between ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) lesions. METHODS: Ninety-four women with 94 lesions diagnosed as breast cancer by surgery underwent IRB-approved preoperative mag...
Source: Magnetic Resonance in Medical Sciences - Category: Radiology Tags: Magn Reson Med Sci Source Type: research
Abstract PURPOSE: Primary endocrine therapy for ductal carcinoma in situ (DCIS) as a potential alternative to surgery has been understudied. This trial explored the feasibility of a short-term course of letrozole and sought to determine whether treatment results in measurable radiographic and biologic changes in estrogen receptor (ER)-positive DCIS. PATIENTS AND METHODS: A phase II single-arm multicenter cooperative-group trial was conducted in postmenopausal patients diagnosed with ER-positive DCIS without invasion. Patients were treated with letrozole 2.5 mg per day for 6 months before surgery. Breast magne...
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: J Clin Oncol Source Type: research
Conclusions The combined radiomics features from DCE-MRI and ADC data may serve as potential predictor markers for predicting PCR. The nomogram could be used as a quantitative tool to predict PCR.
Source: Journal of Computer Assisted Tomography - Category: Radiology Tags: Breast Imaging Source Type: research
Conclusion: The present study, confirms literature data about MRI accuracy in diagnosing HER2+ and triple negative tumors, but suggests caution in case of luminal tumors' evaluation.
Source: In Vivo - Category: Research Authors: Tags: Clinical Studies Source Type: research
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