Comparison of platelet-rich fibrin (PRF) produced using 3 commercially available centrifuges at both high (~  700 g) and low (~ 200 g) relative centrifugation forces

ConclusionsThe present study demonstrated the reproducibility of a scientific concept (reduction in RCF produces PRF clots with more evenly distributed cells and growth factors) utilizing different devices. Furthermore, (and until now overlooked), it was revealed for the first time that the centrifugation tubes are central to the quality production of PRF. Future research investigating tube characteristics thus becomes critically important for the future optimization of PRF.Clinical relevanceThis is the first study to reveal the marked impact of centrifugation tubes on the final production of PRF. Future study thus becomes markedly important to further optimize the quality of PRF-based matrices. It was further found that little variability existed between the centrifugation devices if optimized centrifugation protocols (lower centrifugation speeds) were utilized.

Source: Clinical Oral Investigations - February 21, 2020 Category: Dentistry Source Type: research