Chemo-selective Rh-catalysed hydrogenation of azides into amines.

Chemo-selective Rh-catalysed hydrogenation of azides into amines.
Carbohydr Res. 2020 Feb 06;489:107948
Authors: Ghirardello M, Ledru H, Sau A, Galan MC
Abstract
Rh/Al2O3 can be used as an effective chemo-selective reductive catalyst that combines the mild conditions of catalytic hydrogenation with high selectivity for azide moieties in the presence of other hydrogenolysis labile groups such as benzyl and benzyloxycarbonyl functionalities. The practicality of this strategy is exemplified with a range of azide-containing carbohydrate and amino acid derivatives.
PMID: 32062397 [PubMed - as supplied by publisher]

Source: Carbohydrate Research - February 5, 2020 Category: Genetics & Stem Cells Authors: Ghirardello M, Ledru H, Sau A, Galan MC Tags: Carbohydr Res Source Type: research