Reduced hypertrophy in vitro after chondrogenic differentiation of adult human mesenchymal stem cells following adenoviral SOX9 gene delivery

Mesenchymal stem cell (MSC) based-treatments of cartilage injury are promising but impaired by high levels of hypertrophy after chondrogenic induction with several bone morphogenetic protein superfamily member...

Source: BMC Musculoskeletal Disorders - February 17, 2020 Category: Orthopaedics Authors: M. Weissenberger, M. H. Weissenberger, F. Gilbert, J. Groll, C. H. Evans and A. F. Steinert Tags: Research article Source Type: research