Macrocyclization via C-H functionalization: a new paradigm in macrocycle synthesis

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/C9OB02765C, Review Articlesaumitra sengupta, G Mehta Abstract: The growing emphasis on macrocycles in engaging difficult therapeutic targets such as protein-protein interactions and GPCRs via preferential adaptation of bioactive and cell penetrating conformations has provided impetus to... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research