Pre-Eclampsia and platelets

Patient comes in for induction of labor for pre-eclampsia without severe features. They get a CBC on arrival. Platelets are 300. How long is that number valid for you for neuraxial placement? What’s your cut off time for needing a repeat draw? What if pre-E with severe features? There’s no institutional policy at my place, just provider discretion. Just trying to get a feel for what others are doing.
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Anesthesiology Source Type: forums

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Hypertensive disorders in pregnancy, specifically pre-eclampsia and eclampsia (PE/E), are the second biggest killer of pregnant women globally and remains the least understood and most challenging maternal mor...
Source: Reproductive Health - Category: OBGYN Authors: Tags: Commentary Source Type: research
Gestational diabetes mellitus (GDM) is a common complication of pregnancy associated with significant maternal and neonatal morbidities, including increased risk of pre-eclampsia, macrosomia, and subsequent type 2 diabetes.[1] In most developed countries, universal glucose testing is performed at 24-28 weeks ’ gestation to identify women with overt glucose intolerance.[2] Ideally, women at high risk of developing GDM would be identified earlier in pregnancy to facilitate preventive intervention, enhance antenatal care, and improve clinical outcomes through reduced maternal and fetal exposure to metabo lic alterations...
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
CONCLUSIONS: The fetal lungs associated with GDM/PE and gestational age could be distinguished by ultrasound-based radiomics technology. This supports further research to explore the use of this technology to predict neonatal respiratory complications in women with PE, GDM or their combination. This article is protected by copyright. All rights reserved. PMID: 32250510 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
Pre-eclampsia was associated with a slightly increased risk of epilepsy, autism and other neurodevelopmental problems in offspring.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Preeclampsia Pregnancy and Childbirth Autism Epilepsy Ears and Hearing Intellectual Disabilities Source Type: news
This article reviews sex differences in stroke risk and presentation, with a particular emphasis on the unique risk factors women experience throughout the lifespan. RECENT FINDINGS Although prior studies suggested women have worse outcomes after stroke, it is now clear that age, prestroke functional status, and comorbidities explain many of the differences between men and women in stroke severity, functional outcomes, and mortality. Several meta-analyses and large cohort studies have evaluated the risk factors for women related to reproductive factors and found that fewer years between menarche and menopause, pregnancy...
Source: CONTINUUM: Lifelong Learning in Neurology - Category: Neurology Tags: REVIEW ARTICLES Source Type: research
Abstract Ling and colleagues (BJOG 2020 xxxx) have contributed important information on cardiovascular (CV) assessment over the course of pregnancy, with and without aspirin treatment, associated with risk of pre-term pre-eclampsia, as assessed by the multivariable competing risks model at 11-13 weeks. There are a number of important messages in these data. First, women at low- (vs. high-) risk of preterm pre-eclampsia appear to have lower cardiac output (CO), stroke volume (SV), and blood pressure (BP) in early pregnancy, consistent with the hypothesis that maternal CV predisposition plays a major role in pre-ecl...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: BJOG Source Type: research
Authors: Li M, Qian L, Yu J, Zou Y Abstract Objectives: The protective effects of interleukin(IL)-35 against injury to human umbilical vein endothelial cells (HUVECs) induced by the serum of pre-eclampsia patients were analyzed.Methods: This cross-sectional study included 24 patients with pre-eclampsia (PE) and 24 normotensive pregnant women.Results: Compared to normotensive pregnant women, patients with pre-eclampsia had lower IL-35 levels (P
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
This article addresses the pathophysiology, clinical presentation, diagnostics, treatment, and nursing considerations associated with each uncommon cause of noncardiogenic pulmonary edema.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature: RESPIRATORY DISEASE: CE Connection Source Type: research
Condition:   Antiphospholipid Antibody Syndrome in Pregnancy Intervention:   Other: To study the prognostic value on the occurrence of pre-eclampsia, ADAMTS13 (ADAMTS13 protein and autoantibodies) in patients diagnosed with oAPS Sponsor:   Centre Hospitalier Universitaire de NÄ«mes Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionThis study showed a high rate of adverse obstetrical complications without significant impact on live birth rates. Pregnancy did not appear to influence TAK disease activity.Key Points•We observed a high rate of adverse obstetrical complications in women with Takayasu arteritis; however, the rate of live births was high.Pregnancy did not appear to influence TA disease activity.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
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