Use of Anti-Tumour Necrosis Factor-Alpha Agents in the Management of HLA-B-27-Associated Uveitis: The First Case Series from India.

Conclusion: ADL/GLM is a useful therapeutic option in refractory cases of HLA-B-27-associated uveitis, especially in patients with associated systemic manifestations. PMID: 32058826 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

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ConclusionsThe prevalence and impact of medical comorbidity on PROs are very high in patients with PsA.
Source: Rheumatology and Therapy - Category: Rheumatology Source Type: research
AbstractThe present study aimed to evaluate the clinical efficacy of Andersson lesion (AL) treatments and prognostic factors using medium ‐ to long‐term follow‐up data and discuss the clinical characteristics and treatment of AL. Forty‐eight consecutive AL cases at our center from June 2011 to March 2018 were retrospectively analyzed, including 13 cases treated conservatively and 35 treated surgically. Epidemiological characte ristics, treatment modalities, clinical features and outcomes, and prognostic factors of the Japanese Orthopaedic Association (JOA) recovery rate were reviewed. Neurological functional recove...
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
CONCLUSIONS: IgA antibodies against CD74 are not only markers of AS, but are associated with structural damage development in the sacroiliac joints and in the spine. PMID: 32242816 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: Debusschere C, De Schepper S, Piette Y, Vanhaecke A, Verbist C, Smith V PMID: 32242807 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: Baraliakos X, Hermann KA, Xu S, Hsia EC, Braun J Abstract OBJECTIVES: We aimed to assess relationships between single Bath Ankylosing Spondylitis Metrology Index (BASMI) components and corresponding spinal segment magnetic resonance images (MRI) in anti-tumour-necrosis-factor-treated AS patients. METHODS: Using available MRI and BASMI data from the GO-RAISE trial (n=91 patients), MRI scores for active inflammatory (ASspiMRI-a) and chronic structural (ASspiMRI-c) changes in cervical and lumbar spine segments were compared with BASMI cervical (cervical-rotation [CR] angle, tragus-to-wall [TTW] distance) ...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Source: Neurological Sciences - Category: Neurology Source Type: research
Condition:   Active Sacroiliitis in Ankylosing Spondylitis Intervention:   Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionAlthough no significant protective effect of TNFi treatment on spinal radiographic progression was seen over the course of 2 years or ≥4 years in patients with axial SpA, our analysis restricted to studies with a low risk of bias showed a protective effect of TNFi after ≥4 years. Therefore, long‐term TNFi exposure might confer beneficial effects on spinal radiographic progression in axial SpA. No difference in radiographic p rogression at 2 years was seen in either the NSAID or secukinumab treatment groups compared to their controls. Future studies should explore the effects of biologic treatment on radio...
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Review Source Type: research
AbstractThere are contradictory results in the relevant literature about the relationship between objective determinants of craniocervical posture and temporomandibular disorder (TMD), whereas no study has worked on ankylosing spondylitis (AS) and TMD relationship. We conducted this study to test the predictors of TMD in AS patients and its relationship with craniocervical posture. AS patients aged between 18 and 50  years consecutively admitted to our outpatient clinics were recruited. TMD was diagnosed by ‘Diagnostic Criteria for Temporomandibular Disorders (DC/TMD)’. Spinal mobility was assessed by BASM...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Publication date: Available online 5 March 2020Source: Joint Bone SpineAuthor(s): Gonçalo Boleto, Yannick Allanore, Julien Wipff
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
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