Systematic Review of Light-Based Treatments for Hidradenitis Suppurativa

Publication date: Available online 14 February 2020Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): T. Gracia Cazaña, L.V. Berdel Díaz, J.I. Martín Sánchez, I. Querol Nasarre, Y. GilaberteAbstractTreatment options for hidradenitis suppurativa include light-based therapy. This systematic review aimed to update our understanding of the efficacy, effectiveness and safety of these treatments for hidradenitis suppurativa by evaluating the literature published since the 2015 Cochrane review on this topic. We conducted an electronic search of the following databases: MEDLINE, EMBASE, University of York Centre for Reviews and Dissemination database, Cochrane Database of Systematic Reviews, Cochrane Skin Group Specialised Skin Register, University of Nottingham’s Centre of Evidence Based Dermatology database, and TESEO. The systematic review included 6 case series, 3 systematic reviews, and 2 clinical trials on the use of conventional and intralesional photodynamic therapy, intense pulsed light therapy, and Nd:YAG, carbon dioxide, and diode laser therapy for hidradenitis suppurative in 248 patients.ResumenLa terapia con luz es una alternativa en el tratamiento de la hidradenitis supurativa (HS). El objetivo fue evaluar la eficacia, efectividad y seguridad de las distintas modalidades de terapia con luz en la HS, mediante una revisión sistemática actualizando la realizada en 2015 procedente de Cochrane Library. Se id...
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research

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rd FJ Abstract Pain and discomfort are important symptoms in dermatology. The aim of this cross-sectional, multicentre study was to describe the prevalence of pain/discomfort and its associations in patients with several dermatological conditions across 13 European countries. The outcome was the prevalence of pain/discomfort according to a question of the EQ-5D questionnaire. Data collected from November 2011 to February 2013 were complete for 3,509 consecutive outpatients. Moderate or extreme pain/discomfort was reported by 55.5% of patients and 31.5% of controls with no skin conditions. The highest proportions w...
Source: Acta Derm Venereol A... - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
Rationale: Surgical treatment of hidradenitis suppurativa (HS) is challenging. Wide excision of affected lesions followed by skin graft or flap coverage has been recommended to achieve remission and prevent recurrence. Herein, we present our experience of bilateral inferomedial gluteal defects coverage using symmetrical keystone flaps (KFs) designed parallel to relaxed skin-tension lines (RSTLs). Patient concerns: An 18-year-old man was admitted for chronic inflammatory lesions in both inferomedial gluteal areas. Diagnoses: Physical examination revealed multiple sinuses with broad surrounding scars in both inferome...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Publication date: Available online 29 March 2020Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): M.J. Sánchez-Pujol, P. Álvarez-Chinchilla, A. Docampo-Simón, J.C. Pascual Ramírez
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research
Abstract White fibrous papulosis of the neck is a rare entity, with fewer than 50 cases described. It is a benign pathology whose main interest lies in its broad differential diagnosis, especially with pseudoxanthoma elasticum. The authors report the case of a 77-year-old woman with multiple yellow-white monomorphic papules on the posterior cervical region, with years of evolution. Cutaneous biopsy revealed a nodular area in the superficial and middle reticular dermis, with slight thickening of the collagen fibers and focally enlarged elastic fibers, aspects highlighted in the Verhoeff staining that additionally showed abs...
Source: Anais Brasileiros de Dermatologia - Category: Dermatology Source Type: research
Condition:   Hidradenitis Suppurativa Interventions:   Procedure: Excision of HS followed by NPWTi;   Procedure: Excision of HS followed by NPWT Sponsors:   Royal Free Hospital NHS Foundation Trust;   KCI Europe Holding B.V. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity. The pilosebaceous unit is a site for production and metabolism of a number of steroid hormones, including stress and sex hormones. This is an overview of the important role that the cutaneous HPA-like-axis plays in the pathogenesis and treatment of inflammatory pilosebaceous disorders, including acne, rosacea, seborrheic dermatitis, and hidradenitis suppurativa.
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
We present a 26-year-old man with a history of pemphigus foliaceus (PF) who developed large draining nodules with scarring and sinus tracts, compatible with follicular occlusion triad, preferentially at areas previously affected by PF thirteen months after treatment with rituximab. To the authors' knowledge there are no reported cases of follicular occlusion triad or HS manifesting as an isotopic response. However, one member of the triad, HS, has been reported to occur infrequently following the use of biologic agents...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
CONCLUSIONS: The description of discharge symptoms experienced by many patients is similar to the description of symptoms of an umbilical pilonidal sinus (UPS). This is a condition with a morphology reminiscent to that of HS because it is defined by sinus tract formation triggered by hair penetrating the umbilical skin. UPS could be an explanation for umbilical HS symptom. PMID: 32206815 [PubMed - in process]
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - Category: Dermatology Tags: Acta Dermatovenerol Alp Pannonica Adriat Source Type: research
Nasarre I, Gilaberte Y Abstract Treatment options for hidradenitis suppurativa include light-based therapy. The aim of this study was to evaluate the efficacy, effectiveness, and safety of different light-based treatments for hidradenitis suppurativa in a systematic review updating the 2015 Cochrane review on this topic. We conducted an electronic search of the following databases: MEDLINE, EMBASE, University of York Centre for Reviews and Dissemination database, Cochrane Database of Systematic Reviews, Cochrane Skin Group Specialised Skin Register, University of Nottingham's Centre of Evidence Based Dermatology ...
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Authors: Tags: Actas Dermosifiliogr Source Type: research
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