Steroid Induced Glaucoma: epidemiology, pathophysiology and clinical management
Glucocorticoids are a class of anti-inflammatory drugs commonly used to treat various ocular and systemic conditions. Although the pivotal role of glucocorticoids in the treatment of numerous serious inflammatory diseases, their prolonged use may increase intraocular pressure resulting in steroid-induced glaucoma (SIG).We provide a detailed update on SIG as a preventable cause of blindness in the adult and pediatric population and describe its epidemiology, social impact, and risk factors. Furthermore, we explore the propensity of different steroids to increase the intraocular pressure, the role of different routes of steroid administration, dosage and duration of treatment, as well as the clinical features, genetic and management of SIG.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Gloria Roberti, Francesco Oddone, Luca Agnifili, Andreas Katsanos, Manuele Michelessi, Leonardo Mastropasqua, Luciano Quaranta, Ivano Riva, Lucia Tanga, Gianluca Manni Tags: Major review Source Type: research