Wales has the UK ’s highest prevalence of diabetes

Total for UK now over 4.8 million including undiagnosed cases – predicted to reach 5.3 million by 2025, warns Diabetes UK Related items fromOnMedica Type 2 diabetes in 10 times more young people than realised Child type 2 diabetes is a ‘wake-up call’ to the nation Put children ’s health, not private profits, at heart of policy Diabetes will soon cost NHS £16.9bn Scotland reveals target of halving child obesity by 2030
Source: OnMedica Latest News - Category: UK Health Source Type: news

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CONCLUSIONS: A significant positive correlation exists between HDI and obesity. As policy-makers attempt to improve the general welfare of the people, they should be aware of potential unwanted effects of development on the risk of obesity and overweight among the population. PMID: 32268464 [PubMed - as supplied by publisher]
Source: Journal of Preventive Medicine and Public Health - Category: International Medicine & Public Health Tags: J Prev Med Public Health Source Type: research
AbstractFrustratingly, disease-modifying treatments for diabetic neuropathy remain elusive. Glycaemic control has a robust effect on preventing neuropathy in individuals with type 1 but not in those with type 2 diabetes, which constitute the vast majority of patients. Encouragingly, recent evidence points to new metabolic risk factors and mechanisms, and thus also at novel disease-modifying strategies, which are desperately needed. Obesity has emerged as the second most important metabolic risk factor for neuropathy (diabetes being the first) from consensus findings of seven observational studies in populations across the ...
Source: Diabetologia - Category: Endocrinology Source Type: research
Conditions:   Overweight;   Obesity Intervention:   Other: Normal weight and overweight adults Sponsor:   Liverpool Hope University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Evidence suggests that pathophysiological conditions such as obesity and type 2 diabetes (T2D) are associated with morphologic and metabolic alterations in the small intestinal mucosa. Exploring these alterati...
Source: Diabetology and Metabolic Syndrome - Category: Endocrinology Authors: Tags: Research Source Type: research
We examined the associations between the four PGSs and changes in fasting glucose, insulin, β-cell function (HOMA-B) and insulin resistance (HOMA-IR) in 692 overweight participants (84% white Americans) who were randomly assigned to one of four weight-loss diets in a 2-year intervention trial.ResultsHigher BMI+WHR −PGS was associated with a greater decrease in 2-year changes in waist circumference in white participants (P = 0.002). We also found significant interactions between WHRonly+PGS and dietary protein in 2-year changes in fasting glucose and HOMA-B (P = 0.0007 and 
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
Pulmonary arterial hypertension (PAH) is characterised by progressive obliteration of the pulmonary vasculature, culminating in right-sided heart failure (HF). In recent years, studies have observed an association between systemic metabolic dysfunction, PAH and right ventricular failure [1]. Patients with PAH have an increased prevalence of obesity [2] and type 2 diabetes [3, 4]. Interestingly, abnormal glucose metabolism is evident even in non-diabetic individuals with PAH [5–7], and serves as an independent predictor of prognosis [8].
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Editorials Source Type: research
Publication date: Available online 7 April 2020Source: Academic PediatricsAuthor(s): Marcela Osorio, Christian A. Koziatek, Mary Pat Gallagher, Jessie Recaii, Meryle Weinstein, Lorna E. Thorpe, Brian Elbel, David C. Lee
Source: Academic Pediatrics - Category: Pediatrics Source Type: research
We describe the mechanistic basis for the clinical benefits associated with nutritional ketosis and identify areas of practice where the evidence base could be improved. We summarize the key principles which inform our approach to treating patients with low-carbohydrate diets. The scientific controversy relating to these diets is real but is consistent with the known challenges of any dietary interventions and also the limitations of nutritional epidemiology. Secondly, notwithstanding any controversy, international guidelines now recognize the validity and endorse the use of these diets as a therapeutic nutritional approac...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
AbstractPurposeThe utility of available scoring systems for type 2 diabetes (T2D) remission prediction after metabolic surgery has not been defined in a multi-ethnic Asian population like Singapore. We sought to assess the predictive performance of the Asia-developed ABCD scoring system for T2D remission after metabolic surgery, and develop a new algorithm to improve prediction.Materials and MethodsWe conducted a retrospective analysis of adults with T2D who underwent either Roux-en-Y gastric bypass or sleeve gastrectomy between 2007 and 2018, and followed for 1  year postoperatively (n = 114, mean age 4...
Source: Obesity Surgery - Category: Surgery Source Type: research
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