Ex vivo nail infection as an effective preclinical method for screening of new topical antifungals

This study concludes that the ex vivo porcine hoof model is an effective alternative method for preclinical screening of drugs or new topical compounds developed to combat onychomycosis. Further studies are need to compare the permeability of porcine hooves with human nails permeability.
Source: Journal of Medical Mycology - Category: Biology Source Type: research