Optimal Identification of Human Conventional and Non-conventional (CRTH2-IL7R α-) ILC2s Using Additional Surface Markers

We identified top GATA3-correlated cell-surface expressed genes in human ILCs by RNA-seq. The new surface markers such as CD30 and TNFR2 identified a previously unrecognized human ILC2 population, which is likely to contribute to asthma.

Source: Journal of Allergy and Clinical Immunology - February 3, 2020 Category: Allergy & Immunology Authors: Sucai Liu, Kapil Sirohi, Mukesh Verma, Jerome McKay, Lidia Michalec, Anand Sripada, Tomas Danhorn, Donald Rollins, James Good, Magdalena M. Gorska, Richard J. Martin, Rafeul Alam Source Type: research