miR-425-5p improves inflammation and septic liver damage through negatively regulating the RIP1-mediated necroptosis

ConclusionsThe data suggest miR-425-5p negatively controls the RIP1-mediated necroptotic signaling cascades and inflammation, and sepsis-related liver damage. miR-425-5p/RIP1 axis is a potential therapeutic strategy for sepsis-related liver damage through necroptosis and inflammation.
Source: Inflammation Research - Category: Research Source Type: research