Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study

AbstractCarboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication should be strongly considered.
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research