Incidence of Acute Kidney Injury after Adrenalectomy in Patients with Primary Aldosteronism.

Conclusion: Incidence and risk of postoperative AKI were significantly higher in PA patients after surgical treatment. High ACR on the tumor side and high LI were associated with higher risk of AKI in PA patients compared to pheochromocytoma patients. PMID: 31969923 [PubMed]
Source: Electrolyte and Blood Pressure - Category: Internal Medicine Tags: Electrolyte Blood Press Source Type: research

Related Links:

Conclusions: The development of a pheochromocytoma from an adrenal non functional adenoma is an extremely rare event, but potentially life-threating because of the catecholamine-associated cardiovascular toxicity. In particular, TTS is a form of cardiomyopathy that has been increasingly described as associated with catecholamine-secreting tumors. The exclusion of pheochromocytoma in a patient with TTS has important therapeutic implications, since the administration of β-blockers may be extremely harmful in patients with catecholamine surge in the absence of adequate α-blockage.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Novák K, Michalský D, Widimský J, Zelinka T Abstract CONTEXT: Impaired diurnal blood pressure (BP) variability is related to higher cardiovascular risk. OBJECTIVE: To assess diurnal variability of BP and its relation to target organ damage (TOD) and catecholamine phenotype in a consecutive sample of pheochromocytoma/paraganglioma (PPGL). DESIGN: We included 179 patients with PPGL (96 females). All patients underwent 24h ambulatory blood pressure monitoring (SpaceLabs 90207) to determine dipping status. Differences in plasma metanephrine or urine adrenaline were used to distinguish c...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
ConclusionsThis case illustrates that intra-articular glucocorticoid administration can induce a pheochromocytoma crisis and an increase in hyperglycemia, and that pheochromocytoma crisis can resemble the clinical picture of fulminant type 1 diabetes mellitus owing to severe hyperglycemia with metabolic acidosis and normal glycosylated hemoglobin levels, especially under the influence of glucocorticoid.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Conclusions: Hypotension occurs in 30% patients and hypoglycemia in 15% after pheochromocytoma surgery. Hypotension occurs immediately but hypoglycemia may manifest upto 12h after surgery. Older, diabetic patients are more likely to have persistent HTN. Surgery results in increase in BMI and improvement in QoL.
Source: Indian Journal of Urology - Category: Urology & Nephrology Authors: Source Type: research
Horm Metab Res DOI: 10.1055/a-0754-6464Patients harboring adrenal tumors are characterized by higher prevalence of metabolic syndrome (MetS) components and a higher incidence of cardiovascular complications, especially in cases of subclinical or overt hormonal hypersecretion. Early detection and referral of those patients in tertiary centers could prevent unfavorable outcomes. In this cross-sectional, retrospective study, we evaluated 111 consecutive patients with adrenal incidentalomas and 14 patients with known hypersecretory adrenal lesions (autonomous cortisol secretion, primary aldosteronism, and pheochromocytoma), wh...
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Tags: Endocrine Care Source Type: research
Authors: Murai N, Azami T, Iida T, Mikura K, Imai H, Kaji M, Hashizume M, Kigawa Y, Koizumi G, Tadokoro R, Endo K, Iizaka T, Saiki R, Otsuka F, Norose T, Yamagishi M, Kurokawa I, Oike N, Sasaki H, Nagasaka S Abstract Changes in imaging findings and hormone levels before and after pheochromocytoma rupture, as well as detailed histopathology of resected tumors, have rarely been reported. A 52-year-old woman developed hypertension and diabetes mellitus in 2014, but despite treatment with antihypertensive and hypoglycemic drugs, good control was not achieved. On April 2, 2016, the patient started to have headaches and ...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
Hemodynamic, sugar and metabolic fluctuations occur after surgery for pheochromocytoma and some patients may have complete resolution of hypertension (HTN) and diabetes (DM) with changes in body-mass index (BMI), all of which could impact their quality of life (QoL). We evaluated the trends of such changes in a cohort of patients and assessed factor that could predict them.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Adrenal Source Type: research
ConclusionsOur patient had pheochromocytoma during pregnancy. She had no complaints about hypertension before or during pregnancy until giving birth to her child; her only symptoms were a vague left flank pain, gestational diabetes, and headaches for the past 2  years. The unusual symptom of flank pain led to timely diagnosis and a good treatment outcome.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
We describe the finding of LAM in a 66-year old female presenting with hyperaldosteronism and a 17 mm lesion in the right adrenal gland. The patient displayed secondary hypertension as well as intermittently occurring exaggerated hypertensive episodes with systolic peaks above 220 mm Hg. Preoperative catecholamine screening was negative, diminishing the possibility of a pheochromocytoma. Unilateral adrenalectomy was performed, and histology revealed an aldosterone producing adrenocortical adenoma. No signs of adrenomedullary hyperplasia or pheochromocytoma were found; however, prominent B- and T-lymphocytic i...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - Category: Endocrinology Authors: Tags: Case Report Source Type: research
CONCLUSIONS: Serum CgA is a sensitive and effective noninvasive laboratory test for the clinical detection and management of NETs. Awareness of the pitfalls of the tests in patients with non-NET conditions, particularly chronic diseases and use of certain drugs, is important to be considered during the interpretation of the CgA levels. PMID: 29026467 [PubMed]
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
More News: Diabetes | Endocrinology | Hypertension | Internal Medicine | Pheochromocytoma | Study | Urology & Nephrology