Selective C-H Dithiocarbamation of Drug Skeletons and their Antifungal Activity

Org. Biomol. Chem., 2020, Accepted Manuscript DOI: 10.1039/C9OB02514F, PaperZhuo-Bin Huang, Xiong-Jian Xia, Zi-Hao Huang, Li Xu, Xiaoyong Zhao, Riyuan Tang This paper discloses a metal-free selective C-H dithiocarbamation of drug skeletons using disulfiram (DSF) in the presence of KI/K2S2O8 in DMF/H2O. Drug skeletons, including 5-aminopyrazoles, indoles, pyrroloquinoline, and Julolidine, underwent... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - January 25, 2020 Category: Molecular Biology Authors: Zhuo-Bin Huang Source Type: research