Randomized trial of physiotherapy and hypertonic saline techniques for sputum induction in asthmatic children and adolescents
CONCLUSION: The physiotherapy sputum collection technique was effective in obtaining viable cells from mucus samples and yielded the same amount of sputum as the gold standard technique (hypertonic saline). In addition, the physiotherapy maneuvers were both safe and useful for sputum induction in asthmatic children and adolescents with well-controlled asthma.
Condition: Persistent Asthma Interventions: Combination Product: fluticasone/formoterol k-haler (medium strength); Combination Product: Standard of care (ICs/LABA high strength) Sponsors: Mundipharma Pharmaceuticals S.L.; Alpha Bioresearch S.L.; Dynamic Solutions Not yet recruiting
Condition: Severe Asthma Intervention: Other: No intervention Sponsor: AstraZeneca Recruiting
Household cleaning products could be linked to childhood asthma, research published today suggests. More than five million people in Britain have asthma, including 1.1million children.
ConclusionsAmong uninsured and underinsured asthma patients with GAD and/or MDD who were initiated on a single antidepressant, those who were titrated to achieve target doses had reduced risk of severe asthma exacerbations and lower number of asthma ‐related outcomes than those who were not optimized to achieve target doses.
Publication date: Available online 14 February 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): J.H. Hull, Krystelle Godbout, Louis-Philippe BouletAbstractBreathlessness during sport can be caused by a variety of cardiorespiratory conditions, but when associated with stridor, usually arises from an upper airway etiology. The term exercise-induced laryngeal obstruction (EILO) is now used to describe the phenomonen of transient glottic closure occurring in association with physical activity.Exercise related laryngeal closure is most commonly encountered in athletic individuals and likely affe...
ConclusionsOur results identify specialty specific concerns and can be used to inform the development of tailored interventions to improve wellness and minimize burnout. However, future surveys with a larger sample size are needed to obtain a more robust data set on allergy and immunology specific wellness challenges.
Authors: Doyen V, Casset A, Divaret-Chauveau A, Khayath N, Peiffer G, Bonniaud P, Dalphin JC, De Blay F Abstract Allergy is a hypersensitivity reaction induced by immunological mechanisms. In asthma, allergy has a complex role and is usually IgE mediated. Allergy must be evaluated during the work up but evidence of IgE sensitivity does not mean that allergens play a role in the pathophysiology of the disease. The clinical relevance of the sensitivity has to be considered. This paper describes current available tools to screen for IgE sensitivity, allergen exposure and their role in asthma. PMID: 32057505 [PubMe...
Authors: Raherison C, Hamzaoui A, Nocent-Ejnaini C, Essari LA, Ouksel H, Zysman M, Prudhomme A, groupe de travail Femmes et poumons de la SPLF Abstract In a woman's life, asthma can affect her in a variety of ways, with the onset of premenstrual asthma currently under-diagnosed. It is estimated that about 20% of women with asthma have premenstrual asthma, which is more common in patients with severe asthma. Women with asthma are at high risk of exacerbations and of severe asthma. Asthma is the most common chronic disease during pregnancy with potential maternal and foetal complications. Asthma medications are safe ...
Publication date: 15 February 2020Source: New Scientist, Volume 245, Issue 3269Author(s): Jessica Hamzelou