No Concluding Evidence on Optimal Activated Clotting Time for Non-cardiac Arterial Procedures

Heparin has a non-predictable effect in the individual patient. The activated clotting time (ACT) is used to measure the level of anticoagulation after administration of heparin. To date, appropriate heparin dose protocols and corresponding therapeutic ACT values have not been established in non-cardiac arterial procedures (NCAP). The aim of this review was to study the use of ACT monitoring during NCAP, and whether an optimal ACT could be determined based on the fewest arterial thrombo-embolic complications (ATEC) and bleeding complications.

Source: Journal of Vascular Surgery - January 22, 2020 Category: Surgery Authors: O. Doganer, A.M. Wiersema, V. Scholtes, J.D. Blankensteijn, K.K. Yeung, V. Jongkind Source Type: research