Heavy chain dimers stabilized by disulfide bonds are required to promote in vitro assembly of trastuzumab

Monoclonal antibodies (mAbs) and their derivatives have become one of the most important classes of therapeutic drugs. Their multiple applications increased the interest for understanding their complex structu...

Source: BMC Cell Biology - January 21, 2020 Category: Cytology Authors: Merc è Farràs, Ramón Román, Marc Camps, Joan Miret, Óscar Martínez, Xavier Pujol, Antoni Casablancas and Jordi Joan Cairó Tags: Research article Source Type: research