Phosphoinositides in cell proliferation and metabolism

Publication date: Available online 20 January 2020Source: Advances in Biological RegulationAuthor(s): Emilio Hirsch, Federico Gulluni, Miriam MartiniAbstractPhosphoinositides (PI) are key players in many trafficking and signaling pathways. Recent advances regarding the synthesis, location and functions of these lipids have improved our understanding of how and when these lipids are generated and what their roles are in physiology and disease. In particular, PI play a central role in the regulation of cell proliferation and metabolism. Here, we will review recent advances in our understanding of PI function, regulation, and importance in different aspects of proliferation and energy metabolism.

Source: Advances in Biological Regulation - January 20, 2020 Category: Biology Source Type: research