Transcatheter aortic valve implantation improves cognitive function associated with increased cerebral blood flow in elderly patients with severe aortic stenosis.

CONCLUSIONS: These results provide the first evidence that TAVI may improve cognitive functions associated with increased cerebral perfusion especially in the hippocampus in elderly patients with severe AS. PMID: 31951203 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

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Authors: Kim MY, Park EA, Lee W, Lee SP Abstract OBJECTIVE: To determine the most valuable cardiac magnetic resonance feature tracking (CMR-FT) parameters for evaluating aortic stenosis (AS) and determine whether they can predict the prognosis in asymptomatic AS patients with preserved ejection fraction (pEF). MATERIALS AND METHODS: A prospective cohort of 123 moderate to severe AS patients (60 males, 68.6 ± 9.2 years) and 32 control subjects (14 males, 67.9 ± 4.4 years) underwent echocardiography and 3T CMR imaging from 2011-2015. CMR cine images were analyzed using CMR-FT to assess the left vent...
Source: Korean Journal of Radiology - Category: Radiology Tags: Korean J Radiol Source Type: research
Asymptomatic aortic stenosis (AS) is a challenging disease. Until recently, there was no definitive evidence for early intervention in asymptomatic severe AS, and thus guidelines still incorporate symptom status as a key factor in decision-making.1 Recent prospective data, however, have shown that asymptomatic very severe AS should be treated. Kang et  al.2 reported a randomized controlled trial of 145 patients that showed a clear survival benefit for surgical valve replacement in patients with asymptomatic very severe AS (aortic valve area [AVA] ≤ 0.75 cm2 with either peak velocity ≥ 4....
Source: Journal of the American Society of Echocardiography - Category: Cardiology Authors: Tags: Editorial Comment Source Type: research
ConclusionBoth TTR ‐ and AL‐CA can accompany severe AS. Parameters solely based on ECG and echocardiography allow for the identification of the majority of CA‐AS. In the present cohort, CA did not significantly worsen prognosis 15.3 months after TAVR.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research
Transcatheter aortic valve replacement (TAVR) has become the mainstay of treatment for severe symptomatic aortic stenosis. Despite advances in device technology and procedural techniques, periprocedural stroke remains a severe complication of TAVR, affecting 2% of patients. The embolization of calcific debris from the degenerated aortic valve and atherosclerotic plaque from the aorta, both of which are manipulated during TAVR, is the likely mechanism of periprocedural stroke. Accordingly, cerebral embolic protection devices (EPDs) have been designed to prevent stroke by sequestering embolic debris during TAVR.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research
Publication date: Available online 21 February 2020Source: Canadian Journal of CardiologyAuthor(s): Alexander Emmott, Vanessa Hertig, Alexandre Bergeron, Louis Villeneuve, Laurence Lefebvre, Richard L. Leask, Angelino Calderone, Ismail El-HamamsyAbstractBackgroundClinical studies have revealed a greater risk of pulmonary autograft dilatation after the Ross procedure in patients with preoperative aortic insufficiency (AI). The present study examined whether the morphological, biomechanical and cellular properties of the pulmonary artery (PA) from patients with AI were phenotypically different compared to patients diagnosed ...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Tapping apex Tapping apex is a feature of – Correct Answer: b) Mitral stenosis Tapping apex is thought to be actually the palpable loud first heart sound. Pulmonary stenosis and tricuspid stenosis do not affect the character of the apex beat, being right sided lesions. Aortic stenosis produces a heaving apex beat which is forceful and sustained, due to left ventricular hypertrophy. Back to question
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Medicine MCQ - CVS Source Type: blogs
Tapping apex – MCQ Tapping apex is a feature of : a) Aortic stenosis b) Mitral stenosis c) Pulmonary stenosis d) Tricuspid stenosis Please post your answer as a comment below.
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Medicine MCQ - CVS Source Type: blogs
To assess the phenotypic variations found amongst hearts diagnosed at autopsy with hypoplastic left heart syndrome, with attention to implications related to this syndrome as an acquired disease of fetal life, rather than being the consequence of abnormal embryogenesis. We assessed 119 specimens, from two archives, diagnosed initially as representing hypoplastic left heart syndrome. Among the 119 specimens, the majority of which had been entered into the archives prior to the availability of surgical treatment for the syndrome, 36 (30%) had the combination of mitral and aortic atresia, 26 (22%) had mitral and aortic stenos...
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: CONGENITAL – Original Submission Source Type: research
AbstractSevere aortic stenosis (AS) causes left ventricular (LV) afterload and subendocardial ischemia. Despite this, most infants with AS have normal LV ejection fraction (EF). Strain analysis using two-dimensional speckle tracking echocardiography (2DSTE) may identify more sensitive markers of systolic dysfunction. We sought to show changes in LV strain after balloon aortic valvuloplasty (BAV) in infants with AS. Twenty-seven infants  ≤ 1 year of age with AS who underwent BAV from 2007 to 2017 were included. Echocardiograms before/after BAV were retrospectively analyzed with 2DSTE. Median age was 29...
Source: Pediatric Cardiology - Category: Cardiology Source Type: research
My understanding of the legality and propriety of hospital"advertising" in social media was rather vague but an article on this topic cleared away the cobwebs (see:Hospital Advertising). Below is an excerpt from it. It turns out to be legal but later in the post I will discuss why I think it's beneficial for healthcare consumers.While advertising by doctors and hospitals has been legal for 30 years, until recently, professional taboos discouraged the practice. Increasing economic pressures and changing cultural norms have led, however, to the demise of these informal proscriptions, and advertisements pro...
Source: Lab Soft News - Category: Laboratory Medicine Authors: Tags: Healthcare Business Healthcare Innovations Medical Consumerism Quality of Care Social Media Source Type: blogs
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