Subclassification of Tumor Extension and Nodal Metastasis in Papillary Thyroid Cancer to Improve Prognostic Accuracy of the Eighth Edition of the Tumor –Node–Metastasis Classification
This study investigated methods to further improve the prognostic accuracy of the TNM-8th.MethodsWe enrolled 5683 patients who underwent surgery for PTC at the Kuma Hospital. We subdivided tumor extension (T4a) into T4a1 and T4a2 based on intraoperative gross findings and N1 according to size (
ConclusionThe pathway is a safe and effective service model to manage patients with HNC at low risk for dysphagia during RT, avoiding unnecessary SP appointments for the patient and service.
In this study, a highly sensitive and accurate LC–MS/MS method was firstly established for subsequent measurement of PdG in serum of three different female groups: thyroid cancer patients (TCs), healthy controls (HCs) and pregnant women. The factors affecting the sample preparation, MS/MS method, gradient elution program, selection of chromatographic column and internal standard (IS) have been optimized in this study. Compared with enzyme immunoassay (EIA) method, we used LC–MS/MS to shorten analysis time, increase sensitivity, raise specificity, simplify sample preparation, and reduce costs. As a result, the l...
Conclusions: Evidence-based guidelines were created to assist clinicians in the optimal surgical management of thyroid disease.
Conclusion: Evidence-based guidelines were created to assist clinicians in the optimal surgical management of thyroid disease.
Conditions: Solid Tumor; Medullary Thyroid Cancer Intervention: Drug: Selpercatinib Sponsors: Eli Lilly and Company; Loxo Oncology, Inc. a wholly owned subsidiary of Eli Lilly and Company Not yet recruiting
In conclusion, as the dose rates at a 1-m distance from patients upon release were
This study aims to automatically risk stratify thyroid nodules to determine which nodules need FNA and ultimately reduce the number of unnecessary FNAs. While machine learning has been applied to improve Thyroid Imaging, Reporting, and Data System (TI-RADS) using manually extracted features, to date there has been few applications of machine-learning to automatically classify ultrasound images.
Birt-Hogg-Dubé syndrome (BHDS) is an autosomal dominant genodermatosis characterized by benign cutaneous tumors (fibrofolliculomas, trichodiscomas, and acrochordons), basal lung cysts, pneumothoraces, and a 20% to 30% lifetime risk for renal cancer. There are isolated cases of other cancers in BHDS reported in the literature, including oncocytoma, rhabdomyoma, melanoma, thyroid cancer, meningioma, colon cancer, and breast cancer, but only the increased renal cancer risk has been substantiated. This is the case of a 9-year-old girl who presented with a leiomyosarcoma whose tumor genetic analysis showed FLCN c.365_372...