Luteolin retards CXCL12-induced Jurkat cells migration by disrupting transcription of CXCR4.

In conclusion, luteolin exhibited anti-proliferation and anti-metastasis functions in CXCL12-treated Jurkat cells and inactivated PI3K/AKT and ERK signaling pathways via repressing the transcription of CXCR4.
PMID: 31917965 [PubMed - as supplied by publisher]

Source: Experimental and Molecular Pathology - January 5, 2020 Category: Pathology Authors: Bu Y, Zhao D Tags: Exp Mol Pathol Source Type: research