Effects of orthodontic force magnitude on cell apoptosis and RANKL-induced osteoclastogenesis

ConclusionsEvidence of orthodontic force-induced apoptosis is more robust with stronger forces than with weaker forces. Exuberant RANKL-induced osteoclastogenesis that was seen when applying a  low force results from increased RANK and RANKL expression in the post-lag phase.
Source: Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie - Category: ENT & OMF Source Type: research