Dimers formed with the mixed-type G-quadruplex binder pyridostatin specifically recognize human telomere G-quadruplex dimers

Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/C9OB02470K, PaperTian-Zhu Ma, Meng-Jia Zhang, Ting-Cong Liao, Jun-Hui Li, Min Zou, Zhou-Mo Wang, Chun-Qiong Zhou By adjusting the length of the polyether linkers, pyridostatin (PDS) dimers displayed higher binding selectivities and thermal stabilization towards human telomere antiparallel and mixed-type G-quadruplex dimers (G2T1). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - January 10, 2020 Category: Molecular Biology Authors: Tian-Zhu Ma Source Type: research