Therapeutic effects of AdipoRon on liver inflammation and fibrosis induced by CCl4 in mice.

CONCLUSIONS: AdipoRon demonstrates a remedial capacity against hepatitis and fibrosis induced by CCl4, potentially by inflammation restraint and HSC deactivation, which might pave the way for its therapeutical application in hepatic fibrosis.
PMID: 31911372 [PubMed - as supplied by publisher]

Source: International Immunopharmacology - January 2, 2020 Category: Allergy & Immunology Authors: Sha M, Gao Y, Deng C, Wan Y, Zhuang Y, Hu X, Wang Y Tags: Int Immunopharmacol Source Type: research