Toll-like receptor 4 agonist and antagonist lipopolysaccharides modify innate immune response in rat brain circumventricular organs

The circumventricular organs (CVOs) are blood-brain-barrier missing structures whose activation through lipopolysaccharide (LPS) is a starting point for TLR-driven (Toll-like receptors) neuroinflammation. The ...

Source: Journal of Neuroinflammation - January 6, 2020 Category: Neurology Authors: Alejandra Vargas-Caraveo, Aline Sayd, Javier Robledo-Monta ña, Javier R. Caso, José L. M. Madrigal, Borja García-Bueno and Juan C. Leza Tags: Research Source Type: research