Total synthesis of exigurin: the Ugi reaction in a hypothetical biosynthesis of natural products

Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/C9OB02249J, PaperSeijiro Hosokawa, Keisuke Nakanishi, Yutaro Udagawa, Mitsutoshi Maeda, Seiya Sato, Keiji Nakano, Toshiya Masuda, Yoshiyasu Ichikawa Bioinspired U-5C-4CR employing ( −)-10-epi-axisonitrile-3, formaldehyde and sarcosine in methanol showed remarkable efficiency to assemble multicomponents in a one-pot process, leading to the first total synthesis of exigurin. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - January 6, 2020 Category: Molecular Biology Authors: Seijiro Hosokawa Source Type: research