Targeting the Autonomic Nervous System Balance in Patients with Chronic Low Back Pain Using Transcranial Alternating Current Stimulation: A Randomized, Crossover, Double-Blind, Placebo-Controlled Pilot Study

Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research

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Patients with radicular low back pain (radicular LBP, sciatica) frequently describe their pain as “shooting” or “radiating.” The dictionary meaning of these words implies rapid movement, and indeed, many sufferers report feeling pain moving rapidly from the lower back or buttock into the leg. But, others do not. Moreover, the sensation of movement is paradoxical; it is neither predicted nor accounted for by current ideas about the pathophysiology of radicular LBP. We have used a structured questionnaire to evaluate the sensory qualities associated with “shooting” and “radiating&rdq...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
Condition:   Chronic Low-back Pain Intervention:   Device: Flowly (TMC-CP01) Sponsors:   Aman Mahajan;   National Institutes of Health (NIH);   National Institute on Drug Abuse (NIDA) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Chronic low back pain (cLBP) is a major health problem and the most common pain condition among those aged 60  years or older in the US. Despite the development of pharmacological and nonpharmacological interve...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
According to clinical guidelines, advice to stay active despite experiencing pain is recommended to patients with non-specific low back pain (LBP). However, not all patients receive guideline-concordant inform...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Research article Source Type: research
This study aims to test auricular point acupressure (APA) as a non-invasive, nonpharmacological self-management strateg y to manage cLBP and to address current shortcomings of cLBP treatment.Methods/designFor this prospective randomized controlled study, participants will be randomly assigned to three groups: (1)APA group (active points related to cLBP), (2) Comparison group-1 (non-active points, unrelated to cLBP), and (3) Comparison group-2 (enhanced educational control, an educational booklet on cLBP will be given and the treatment used by participants for their cLBP will be recorded). The ecological momentary assessmen...
Source: Trials - Category: Research Source Type: clinical trials
Most cases of low back pain (LBP) are regarded as non-specific and current studies indicate that for many this is a chronic recurrent condition, in which people experience episodes of pain with symptom-free pe...
Source: Chiropractic and Osteopathy - Category: Complementary Medicine Authors: Tags: Study protocol Source Type: research
A rejection of its experimental pain drug Tuesday forced Nektar Therapeutics Inc. to dump the program. In a rare indisputable rejection, two Food and Drug Administration advisory committees voted 27-0 to recommend that the FDA not approve the San Francisco company's oxycodegol, a slow-acting opioid aimed at chronic lower back pain. The FDA isn't required to live by the advisory committees' recomme ndation, but six hours later Nektar (NASDAQ: NKTR) said it would withdraw its approval request and…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Nektar Therapeutics said on Tuesday it was withdrawing the application for its opioid painkiller for adults with chronic low back pain, after a U.S. Food and Drug Administration (FDA) panel unanimously voted against the drug's approval.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
CONCLUSIONS: The most important variables were the prone instability test, pelvic tilt test, straight leg raise, body weight, visual analogue scale and the short form 36 health survey. PMID: 31929137 [PubMed - as supplied by publisher]
Source: Journal of Back and Musculoskeletal Rehabilitation - Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research
This study aimed to identify the effectiveness of breathing exercises and lumbar segmental exercises on the vital capacity of lumbar instability patients. METHOD: Fifty-nine patients suffering from chronic low back pain participated in this study. They were randomly divided into three groups: experiment group 1 performed breathing and segmental stabilization exercises (n= 20), experiment group 2 performed segmental stabilization exercises (n= 20), and the control group performed the modality treatment (n= 19). The measurements were assessed on vital capacity. RESULTS: The difference in the forced vital capacity, ma...
Source: Journal of Back and Musculoskeletal Rehabilitation - Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research
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