Lack of evidence for a continuum between hepatorenal syndrome and acute tubular necrosis

We read with great interest the review article “News in Pathophysiology, Definition, and Classification of Hepatorenal Syndrome: a step beyond the International Club of Ascites (ICA) Consensus document” by Angeli et al. published recently in Journal of Hepatology.1 The review discusses a number of important issues related to acute kidney inj ury (AKI) in cirrhosis and proposes modifications to the definition, classification, pathogenesis, and management of hepatorenal syndrome (HRS). HRS is a specific type of kidney impairment unique to patients with cirrhosis characterized by a sudden and severe impairment in kidney function in the abs ence of significant histological abnormalities in the kidneys.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research