Therapeutic breakthroughs for metastatic thyroid cancer

Nature Reviews Endocrinology, Published online: 09 December 2019; doi:10.1038/s41574-019-0307-2Multikinase inhibitors are effective treatments for thyroid cancers, acting primarily as antiangiogenic agents. This year, advances have been made in selective targeting of RET and BRAF in patients with medullary and anaplastic thyroid cancers, respectively. However, Hürthle cell carcinomas have a unique genomic landscape with no dominant truncal drivers, precluding simplistic approaches to therapeutic targeting.
Source: Nature Reviews Endocrinology - Category: Endocrinology Authors: Source Type: research