Differences in PD-L1-Expressing Macrophages and Immune Microenvironment in Testicular Germ Cell Tumors.

CONCLUSIONS: Robust PD-L1+ TAMs are significantly expanded in seminomas compared with NSGCTs. Among all GCTs, only choriocarcinoma cells reveal true positivity for PD-L1. These findings expand the realm of potentially targeted treatments for GCTs.
PMID: 31802108 [PubMed - as supplied by publisher]

Source: American Journal of Clinical Pathology - December 4, 2019 Category: Pathology Authors: Sadigh S, J Farahani S, Shah A, Vaughn D, Lal P Tags: Am J Clin Pathol Source Type: research