Celiac disease in Saudi children with isolated short stature: is it rare or are we not screening rigorously enough?

Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research

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Publication date: Available online 26 January 2020Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Hamed Esmaeil Lashgarian, Maryam Karkhane, Abdolrazagh Marzban, Mohammad Yazdi, Kiana ShahzamaniAbstractGastrointestinal (GI) disorders including a wide range of infectious, inflammatory, autoimmune, etc. disorders. Inflammatory bowel and celiac disease are non-fatal but overwhelming GI associated disorders. IBD and celiac’s complications, besides the great suffering, disturb the normal life of the patients and make them involved in mental and physical problems. The emerging role of genetic...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
Authors: Cartee A, Murray JA PMID: 31981420 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
Conditions:   Celiac Disease in Children;   Celiac Disease;   Celiac;   Disclosure;   Stigma, Social;   Emotional Problem;   Mental Health Wellness 1 Intervention:   Other: semi-structured interview Sponsor:   University of Oxford Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Alopecia Areata;   Depressive Episode;   Recurrent Depressive Disorder;   Anxiety Disorders;   Atopic Dermatitis;   Allergic Rhinitis;   Asthma;   Crohn Disease;   Ulcerative Colitis;   Pernicious Anemia;   Type 1 Diabetes;   Hashimoto Thyroiditis;   Graves Disease;   Rheumatoid Arthritis;   Psoriatic Arthritis;   Ankylosing Spondylitis;   Systemic Lupus Erythematosus;   Polymyalgia Rheumatica;   Sjogren's Syndro...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Graft versus host disease (GVHD) causes significant morbidity and mortality after allogeneic stem cell transplant (SCT). Little is known about genetic determinants of GVHD risk, including human leukocyte antigen (HLA) genotypes outside of HLA-mismatch. HLA-DQ2 and DQ8 genotypes are associated with celiac disease (CD) and are present in ≥90% of patients with CD. Both GVHD and CD are systemic inflammatory conditions that may have T cell-mediated enteropathy. We hypothesized HLA-DQ alleles associated with CD risk would confer increased risks of acute (a) and chronic (c) GVHD in pediatric SCT recipients.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 272 Source Type: research
Conclusions: Transition of care for young adults with CD is inconsistent, particularly among asymptomatic patients. Receipt of a referral for an adult provider significantly improves follow-up rates.
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Article: Gastroenterology: Celiac Disease Source Type: research
ConclusionsScurvy is caused by vitamin C deficiency. Cutaneous bleeding, mucosal bleeding, and anemia represent typical manifestations of the disease. These symptoms are directly connected to ascorbic acid involvement in collagen biosynthesis. Some radiographic findings can be useful for the diagnosis. Treatment aims to normalize serum levels of vitamin C in order to counteract the deprivation symptoms. The present case report demonstrates that scurvy may sporadically occur in pediatric patients, even in individuals with no predisposing medical conditions and/or potential risk factors.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Recently, involvement of IL-19, IL-20 and IL-24 has been reported in inflammatory diseases associated with tissue remodeling. However, their impact on the pathomechanism of coeliac disease (CD) is still comple...
Source: Journal of Translational Medicine - Category: Research Authors: Tags: Research Source Type: research
AbstractThe aim of this study is to demonstrate the effectiveness of the gluten-free diet (GFD) for celiac disease (CD) in a multidisciplinary outpatient Gastroenterology clinic with two adult cases using the innovative, paradigm-shifting measurement systems: The NIH Patient reported outcome measures (PROs). CD results in gastrointestinal (GI) dysfunction, but is also associated with other inflammatory responses, psychosocial impairment, and cognitive deficits such as “brain fog.” Adherence to the GFD for 6 months was associated with improvement in specific GI symptoms in one case (PROMIS-GI; Case 2) and improv...
Source: Journal of Clinical Psychology in Medical Settings - Category: Psychiatry & Psychology Source Type: research
ConclusionDistinct gliadin ‐derived peptides elicit different effects on cDC2 phenotype and function. This effect is compatible with a model where diverse gliadin peptides might cooperate to promote full cDC2 activation and the subsequent T‐cell response in genetically predisposed individuals.This article is protected by copyright. All rights reserved
Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Research Article Source Type: research
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