Upregulation of thioredoxin and its reductase attenuates arsenic trioxide ‑induced growth suppression in human pulmonary artery smooth muscle cells by reducing oxidative stress.

In conclusion, upregulation of Trx1 and TrxR1 somewhat decreased cell growth inhibition and death in ATO‑treated HPASMCs, which was accompanied by reduced oxidative stress. PMID: 31789420 [PubMed - as supplied by publisher]
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research