Cerebral Embolic Protection to Prevent Brain Inury in Thoracic Aortic Stent-Grafting (TEVAR)

Introduction - Stroke occurs in 2-8%1 and silent cebebral infraction (SCI) in up to 63%2 of patients undergoing thoracic endovascular aortic repair (TEVAR).
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Source Type: research

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ConclusionsThis multicenter clinical trial describes excellent 5-year outcomes and durable exclusion of blunt thoracic aortic injury using a novel stent graft system. TEVAR with this endograft appears to be a safe and effective treatment option for patients with BTAI.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: February 2020Source: The Annals of Thoracic Surgery, Volume 109, Issue 2Author(s): Elizabeth L. Norton, Xiaoting Wu, Linda Farhat, Karen M. Kim, Himanshu J. Patel, G. Michael Deeb, Bo YangBackgroundIt is controversial if extension of aortic dissection into arch branches should be an indication for replacement of the arch and its branches in acute type A aortic dissection.MethodsFrom 2008 to April 2018, 399 patients underwent open repair for an acute type A aortic dissection, and 190 patients had known innominate and/or left common carotid artery dissection without malperfusion syndrome, including no arch ...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Conclusion:Our findings demonstrate that rTMS treatment and hMSC transplantation could synergistically create a favorable microenvironment for cell survival within the PD rat brain, through alteration of soluble factors such as neurotrophic/growth factors and anti-/pro-inflammatory cytokines related to neuronal protection or repair, with preservation of DA neurons and improvement of motor functions.
Source: Tissue Engineering and Regenerative Medicine - Category: Biotechnology Source Type: research
We report our initial experience with the off-label use of a dual-filter CEPD in patients undergoing TEVAR.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
Delivery of exosomes derived from stem cell populations has been demonstrated to improve recovery from injury in numerous studies and human applications. The interesting aspect of this demonstration in stroke recovery in pigs is that exosomes from neural stem cells provoke greater functional recovery without improving some of the structural changes that are normally associated with greater mortality and loss of function. Researchers have presented brain imaging data for a new stroke treatment that supported full recovery in swine, modeled with the same pattern of neurodegeneration as seen in humans with severe str...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Extracranial carotid artery aneurysm (CAA) is an extremely rare peripheral arterial aneurysm. The treatments of extracranial CAAs include open surgical, endovascular, and conservative options. Main surgical indications are transient ischemia attacks (TIA), strokes or progressive growth. But both open surgery and endovascular repair have disadvantages and complications.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
This study provides strong evidence that following a healthy lifestyle can substantially extend the years a person lives disease-free." Commentary on Recent Evidence for Cognitive Decline to Precede Amyloid Aggregation in Alzheimer's Disease https://www.fightaging.org/archives/2020/01/commentary-on-recent-evidence-for-cognitive-decline-to-precede-amyloid-aggregation-in-alzheimers-disease/ I can't say that I think the data presented in the research noted here merits quite the degree of the attention that it has been given in the popular science press. It is interesting, but not compelling if its role...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Siegfried Richtsteig has been waiting in hospital for more than 130 days for a heart that would allow him to do the things he enjoyed most, like playing with his grandchildren, before a stroke damaged the organ beyond repair.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Transplantation News Source Type: news
Primary and Stem Cell CultureThis just came across our radar." SUPPLEMENTARY MATERIAL An eye opener in stroke: Mitochondrial dysfunction and stem cell repair in MCAO induced retinal ischemia "We are always delighted when researchers supplement their cell culture media with ourFetal Bovine Serum (FBS).RPE Cells and MSC Culture Retinal pigmented epithelium (RPE, CRL-4000; ATCC) cells were cultured in Dulbecco ’s Modified Eagle Media/F-12 (DMEM/F-12, 11320033; Gibco) containing 10% fetal bovine serum (FBS; FBS001; Neuromics) and 0.01 mg/ml hygromycin B (10687010; Gibco) in incubator (37 °C humidified, with...
Source: Neuromics - Category: Neuroscience Tags: adult stem cells FBS Fetal Bovine Serum Human Mesenchymal Stem Cells MSCs Retinal Pigment Epithelial Cells RPES Source Type: news
Siegfried Richtsteig has been waiting in hospital for more than 130 days for a heart that would allow him to do the things he enjoyed most, like playing with his grandchildren, before a stroke damaged the organ beyond repair.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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